What is IGA nephropathy?

IgA Nephropathy, also known as Berger's disease, is a kidney disorder that occurs when an antibody called immunoglobulin A (IgA) builds up in the kidneys. IgA is a type of antibody that plays a role in the immune system's response to infections. In IgA Nephropathy, there is an abnormal deposition of IgA in the glomeruli, which are the filtering units of the kidneys.

In individuals with IgA Nephropathy, the deposited IgA can cause inflammation and damage to the glomeruli, leading to kidney problems.

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Causes Of IGA nephropathy?

The exact cause of IgA Nephropathy is not fully understood, but several factors may contribute to its development. Here are some potential causes and risk factors associated with IgA Nephropathy:

  • Abnormal Immune Response: IgA Nephropathy is believed to result from an abnormal immune system response. The exact trigger for this response is unclear, but it involves the deposition of immunoglobulin A (IgA) in the glomeruli of the kidneys.
  • Genetic Factors: There appears to be a genetic predisposition to IgA Nephropathy, as it often runs in families. Certain genetic factors may influence an individual's susceptibility to developing the condition.
  • Infections: In some cases, IgA Nephropathy may be associated with infections, particularly respiratory or gastrointestinal infections. The immune response triggered by these infections may contribute to the abnormal deposition of IgA in the kidneys.
  • Environmental Factors: Environmental factors, such as exposure to certain toxins or pollutants, may potentially play a role in the development of IgA Nephropathy, although specific causative agents are not well-defined.
  • Other Underlying Health Conditions: Individuals with certain conditions, such as liver diseases and celiac disease, may have an increased risk of developing IgA Nephropathy.
  • Age and Gender: IgA Nephropathy often occurs in young adults, with the peak incidence occurring in the second and third decades of life. It is also more common in males than females.

Symptoms Of IGA Nephropathy

The symptoms of IgA Nephropathy can vary widely, and some individuals may not experience noticeable symptoms in the early stages of the condition. However, common symptoms may include:

  • Blood in the urine (hematuria): This can be the most common and noticeable symptom, making urine appear dark brown, cola-colored, or containing visible blood.
  • Foamy urine (proteinuria): Protein leaks into the urine, causing the characteristic frothy appearance.
  • Flank pain: A dull ache or pain on one or both sides of the back, below the ribs.
  • Swelling (edema): Fluid buildup in the hands, feet, and ankles.
  • High blood pressure (hypertension): Can occur as a result of kidney damage.
  • Less common symptoms: These may include fatigue, nausea, vomiting, and frequent respiratory infections.

Who is at a Higher Risk?

Individuals at Higher Risk for IgA Nephropathy:

  • Young adults (teens to late 30s): This age group shows the highest incidence of the disease.
  • Men: IgA Nephropathy affects men about twice as often as women.
  • Ethnicity: Certain ethnicities have a higher risk, including:
    • Asian descent
    • European descent
    • Native American descent
  • Family history: Having a family member with IgA Nephropathy or IgA vasculitis (Henoch-Schönlein purpura) significantly increases your risk.
  • Specific medical conditions:
    • Celiac disease
    • HIV infection
    • Cirrhosis
    • Liver disease
    • Recurrent upper respiratory infections

How To Diagnose IGA Nephropathy

  • Medical history and physical exam:
    • Discuss symptoms (e.g., blood in urine, high blood pressure, swelling).
    • Review family history of kidney disease.
    • Check for signs of kidney dysfunction or other diseases.
  • Laboratory tests:
    • Urinalysis: Detects blood, protein, and other abnormalities in urine.
    • Blood tests:
      • Assess kidney function (creatinine, eGFR).
      • Check for protein levels (albumin-to-creatinine ratio).
      • Analyze cholesterol and other lipids.
    • Kidney function tests: Measure glomerular filtration rate (eGFR) to assess kidney filtering capacity.
  • Imaging tests:
    • Ultrasound: Visualize kidneys for size and structure abnormalities.
    • CT scan or MRI: Provide detailed images of kidneys and surrounding structures.
  • Kidney biopsy (in some cases):
    • Removes a tiny tissue sample for microscopic analysis.
    • Definitively confirms IgA deposits in the glomeruli, characteristic of IgA nephropathy.

Complications of IGA Nephropathy

While some people with IgA nephropathy experience no complications, others can develop serious issues over time. Here are some potential complications of IgA nephropathy:

  • Kidney damage:
    • High blood pressure: This is a common complication and can further accelerate kidney damage.
    • Chronic kidney disease: This means your kidneys gradually lose their ability to function properly. In severe cases, it can lead to end-stage renal disease (ESRD) or kidney failure.
    • Acute kidney failure: This is a sudden and rapid loss of kidney function, which can be life-threatening.
  • Other complications:
    • Nephrotic syndrome: This is a group of symptoms caused by severe kidney damage. These symptoms can include swelling, high protein levels in urine, high cholesterol, and frothy urine.
    • Heart problems: High blood pressure and other complications can increase your risk of heart attack, stroke, and heart failure.
    • IgA vasculitis: This is a rare condition where IgA deposits damage blood vessels, leading to inflammation and tissue damage.

Ayurvedic Treatment For IGA Nephropathy

Iga nephropathy, a kidney disorder, finds solace in Ayurvedic treatments. Ayurveda, an ancient holistic healing system, offers a unique approach to managing Iga nephropathy. Ayurvedic treatment for Iga nephropathy focuses on restoring balance to the body's energies. Ayurveda employs herbs, lifestyle modifications, and dietary changes to address the root causes of this condition.

Iga nephropathy treatment in Ayurveda involves personalized herbal formulations that aim to rejuvenate the kidneys. These Ayurvedic remedies target the imbalances in the body, promoting overall well-being. Ayurvedic practitioners emphasize the significance of dietary choices, encouraging a kidney-friendly diet to manage Iga nephropathy effectively.

Iga nephropathy Ayurvedic treatment emphasizes the importance of lifestyle adjustments. Incorporating stress-reducing practices and maintaining a disciplined routine contribute to the overall success of Ayurvedic intervention. In the realm of Iga nephropathy treatment Ayurveda stands as a beacon, offering a holistic and personalized approach to healing.

Ayurvedic Medicine For IGA Nephropathy

Here are some Ayurvedic herbs and approaches that are sometimes used in managing kidney conditions, including IgA Nephropathy:

  • Punarnava (Boerhavia diffusa): Known for its diuretic properties, Punarnava is believed to help reduce fluid retention and inflammation.
  • Gokshura (Tribulus terrestris): Used for its potential diuretic and anti-inflammatory effects, Gokshura may support kidney health.
  • Varuna (Crataeva nurvala): Varuna is traditionally used in Ayurveda for its diuretic and anti-inflammatory properties, potentially benefiting the kidneys.
  • Chandraprabha Vati: An Ayurvedic herbal formulation that may include ingredients like Guggulu, Shilajit, and others. It is believed to support kidney function.
  • Shilajit: Rich in minerals and fulvic acid, Shilajit is considered to have rejuvenating properties and may be used in Ayurveda for kidney health.
  • Daruharidra (Berberis aristata): Known for its anti-inflammatory and antioxidant properties, Daruharidra may be beneficial in managing inflammation associated with IgA Nephropathy.
  • Ginger (Zingiber officinale): Ginger is recognized for its anti-inflammatory properties and may be included in Ayurvedic formulations for kidney support.
  • Amla (Emblica officinalis): Amla is rich in vitamin C and antioxidants, and it may have a protective effect on the kidneys.

Why Choose Karma Ayurveda

Holistic Approach: Karma Ayurveda focuses on treating the root cause of IGA Nephropathy, addressing imbalances in the body's systems rather than just managing symptoms.

  • Personalised Treatment: Each patient receives a customised treatment plan based on their individual needs and Ayurvedic principles.
  • Herbal Remedies: Karma Ayurveda utilizes time-tested, natural herbal formulations prepared according to traditional methods to gently support kidney health.
  • Dietary Guidance: Ayurvedic diet plays a crucial role in managing IGA Nephropathy. Karma Ayurveda provides personalized dietary recommendations for optimal kidney function.
  • Lifestyle Modifications: Karma Ayurveda emphasizes lifestyle changes like stress management, yoga, and proper sleep to promote overall well-being and kidney health.
  • Gentle and Safe: Ayurvedic treatments are generally considered safe and gentle, with minimal side effects compared to conventional medications.
  • Complementary Approach: Karma Ayurveda's approach can complement and support conventional treatment, potentially leading to improved outcomes.
  • Focus on Overall Health: Karma Ayurveda promotes not just managing IGA Nephropathy, but also enhancing overall health and well-being.

Certificate no- AH-2023-0186
JAN 05,2023-JAN 04,2026