What is Blood Urea?

Blood urea disease typically refers to an abnormal increase in the concentration of urea in the blood, which is often associated with kidney dysfunction. Urea is a waste product formed in the liver as a result of the breakdown of proteins. It is normally filtered by the kidneys and excreted from the body through urine. However, if the kidneys are not functioning properly, urea can accumulate in the blood.

Elevated blood urea levels may indicate kidney problems or other medical conditions affecting the kidneys. The condition is commonly assessed through a blood test that measures blood urea nitrogen (BUN) levels. BUN is a component of blood urea, and its levels can be an indicator of how well the kidneys are filtering and excreting waste products.

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Causes Of Blood Urea

  • High protein intake: Consuming excessive protein can overwhelm the kidneys' ability to process it efficiently, leading to urea buildup in the blood.
  • Dehydration: When dehydrated, the body conserves fluid by reabsorbing water from urine. This concentrated urine concentrates urea as well, potentially raising blood levels.
  • Kidney disease: Various kidney diseases can impair their ability to filter waste products like urea, causing it to accumulate in the bloodstream.
  • Liver disease: In some liver diseases, protein metabolism is disrupted, leading to increased urea production and potentially elevated blood levels.
  • Gastrointestinal bleeding: Internal bleeding in the digestive tract can release blood into the intestines, where some urea is reabsorbed into the bloodstream, potentially raising levels.
  • Certain medications: Some medications, like diuretics and corticosteroids, can affect kidney function or urea metabolism, potentially leading to elevated blood levels.
  • Dietary restrictions: Crash diets or those severely restricting protein intake can trigger the breakdown of muscle tissue for energy, releasing urea into the bloodstream and potentially raising levels.

Symptoms Of Blood Urea

  • Fatigue and tiredness: Elevated blood urea (BUN) can drain energy, leading to lethargy and difficulty concentrating.
  • Loss of appetite: Nausea and vomiting may occur, causing decreased interest in food.
  • Frequent urination: The body attempts to flush out excess urea through increased urination.
  • Confusion and disorientation: High BUN levels can affect brain function, leading to mental fogginess and confusion.
  • Dry mouth and thirst: Dehydration due to increased urination can cause dryness and excessive thirst.
  • Itchy skin: Urea buildup in the blood can irritate the skin, leading to itching and discomfort.
  • Muscle cramps: Electrolyte imbalances caused by high BUN can lead to muscle spasms and cramps.
  • Edema (swelling): Fluid retention, particularly in the legs and ankles, may occur due to impaired kidney function.

Who is at a Higher Risk?

Here are the people who might be affected by elevated BUN or uremia, depending on the specific situation:

Elevated BUN:

  • People with existing kidney disease: Chronic kidney disease (CKD) and acute kidney injury (AKI) are major risk factors.
  • Individuals with uncontrolled diabetes or high blood pressure: These conditions can damage the kidneys over time.
  • People experiencing dehydration: Lack of fluids can concentrate the blood and raise BUN levels.
  • Individuals on certain medications: Some drugs, like diuretics and corticosteroids, can affect BUN levels.
  • People with gastrointestinal bleeding: This can increase blood ammonia, which is converted to urea, raising BUN levels.
  • Individuals with severe infections or burns: These can cause a catabolic state, breaking down tissues and releasing nitrogen into the blood, raising BUN.


  • Individuals with advanced kidney disease: Uremia is a complication of severe kidney failure.
  • People with certain causes of kidney failure: Diabetes, high blood pressure, and autoimmune diseases are common causes.
  • Individuals with a history of kidney injury or surgery: These can increase the risk of future kidney failure and uremia.
  • People exposed to certain toxins or medications: Some substances can damage the kidneys and lead to uremia.

How To Diagnose Blood Urea

Initial Evaluation:

  • Symptoms: High blood urea (BUN) often doesn't cause specific symptoms, but underlying conditions might. Be alert for fatigue, nausea, vomiting, decreased urination, confusion, and changes in mental state.
  • Medical history: Discuss any existing medical conditions, medications, recent surgeries, or dietary changes that could affect BUN levels.
  • Physical examination: Your doctor will check for signs of dehydration, kidney issues, or other relevant factors.

Laboratory Tests:

  • Blood urea nitrogen (BUN) test: Measures the amount of urea nitrogen in your blood. Elevated BUN levels suggest impaired kidney function or other issues.
  • Serum creatinine test: Creatinine is another waste product filtered by the kidneys. High levels alongside high BUN may indicate kidney disease.
  • Electrolyte panel: Checks for imbalances in electrolytes like potassium and sodium, which can occur alongside high BUN.
  • Glomerular filtration rate (GFR) test: Estimates your kidneys' filtering function, helping determine the cause of elevated BUN.

Further Investigations:

  • Imaging tests: Ultrasounds, CT scans, or MRIs may be used to visualise the kidneys and bladder for abnormalities.
  • Urine tests: Examining urine composition can reveal infections, blood in the urine, or other clues to the cause of high BUN.
  • Kidney biopsy: In rare cases, a small tissue sample from the kidney may be needed for definitive diagnosis.

Complications Of Blood Urea

Complications of High Blood Urea:

  • Uremic encephalopathy: This serious condition occurs when high blood urea levels affect brain function, causing symptoms like confusion, drowsiness, and seizures.
  • Acidosis: Urea buildup can lead to an acidic blood pH (acidosis), disrupting various bodily processes and causing further complications.
  • Weakened immune system: High blood urea can impair the immune system's response to infections, increasing susceptibility to illness.
  • Nutritional deficiencies: Chronic hyperuremia can affect nutrient absorption and utilization, leading to deficiencies in essential vitamins and minerals.
  • Increased risk of cardiovascular events: Studies suggest a potential link between high blood urea and an increased risk of heart disease and stroke.

Ayurvedic Treatment For Blood Urea

Ayurvedic medicine offers an effective approach for reducing blood urea levels. Blood urea treatment in Ayurveda focuses on balancing the body's doshas, primarily targeting elevated urea levels. Ayurvedic practitioners prescribe herbs like Gokshura and Punarnava, renowned for their diuretic properties, aiding in the natural elimination of excess urea. These herbs are integral to blood urea Ayurvedic treatment, promoting kidney health and mitigating urea accumulation. Incorporating lifestyle modifications and dietary adjustments also play a crucial role in Ayurveda. This holistic approach addresses the root cause, making blood urea Ayurvedic treatment a comprehensive and sustainable solution for maintaining renal well-being.

Ayurvedic Medicine To Reduce Blood Urea

Here are some Ayurvedic herbs that are commonly associated with kidney health and may be considered for managing blood urea levels:

  • Punarnava (Boerhavia diffusa): Punarnava is known for its diuretic properties and is believed to help in flushing out toxins from the kidneys. It may be used in Ayurveda to support kidney function and maintain healthy blood urea levels.
  • Gokshura (Tribulus terrestris): Gokshura is traditionally used in Ayurveda to support urinary tract health. It is considered to have diuretic properties and may aid in maintaining normal blood urea levels.
  • Varuna (Crataeva nurvala): Varuna is known for its detoxifying properties and is traditionally used in Ayurveda to support kidney function. It may assist in managing blood urea levels by promoting healthy filtration.
  • Chandraprabha Vati: This Ayurvedic formulation contains a combination of herbs, including Guggulu, Shilajit, and Vacha, among others. It is believed to support kidney health and may help in maintaining balanced blood urea levels.
  • Shunthi (Zingiber officinale): Shunthi, or dried ginger, is known for its anti-inflammatory properties. It may be used in Ayurveda to reduce inflammation in the kidneys and support overall renal health.

Why Choose Karma Ayurveda

  • Holistic Approach: We address the root cause of high blood urea, not just symptoms, with personalized herbal regimens and lifestyle modifications.
  • Experienced Practitioners: Our vaidyas have deep knowledge of Ayurvedic blood purification and kidney health, ensuring safe and effective treatment.
  • Natural Remedies: We use potent Ayurvedic herbs like Punarnava, Gokshura, and Amalaki, known for their diuretic and kidney-supporting properties.
  • Gentle Detoxification: Our treatments gently cleanse the body of toxins and excess urea, promoting natural kidney function.
  • Dietary and Lifestyle Guidance: We provide personalized advice on diet, exercise, and stress management to support your healing journey.
  • Sustainable Results: We focus on long-term management, empowering you with knowledge and tools to maintain healthy blood urea levels.
  • Comprehensive Care: We offer additional therapies like yoga, meditation, and marma therapy to holistically address your well-being.
  • Positive Patient Experiences: We have a track record of success in helping individuals manage high blood urea through Ayurveda.

Certificate no- AH-2023-0186
JAN 05,2023-JAN 04,2026